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Thesis

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Automate AI research

F25·Fall 2025·B2B·San Francisco, CA, USA·Team of 2·Founded 2025

About

We are accelerating AI research and development. Our aim is to help researchers uncover the next AlphaFold or build the next Transformer, faster, more systematically, and at scale. We treat discovery not as a matter of luck, but as an intelligent search problem. By giving researchers access to an autonomous AI research lab, Thesis lets you build powerful machine learning models for anything imaginable. Every major breakthrough in AI over the next decade will be made on Thesis.

Founders

  • Sergio Charles· Co-Founder & CEO

    Thesis will automate AI research. Maximally truth-seeking. Prev: AI R&D at Google X, Nvidia and Stanford's AI Lab, working with Andrew Ng and Chelsea Finn. B.S. Math & CS, M.S. Stats Stanford

  • Luigi Charles· Founder

    Betting the farm that AI will become meaningful in the discovery of new science. Second time founder. Previously scaled stablecoin payments infrastructure from zero to billions. Columbia CS & Math.

Product launches · 1 launch

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