Thesis

About

We are an AI research lab automating AI research. Our aim is to build a hill-climbing machine capable of solving humanity's greatest challenges in science and engineering, uncovering the next AlphaFold or Transformer faster, more systematically, and at scale. We treat discovery not as a matter of luck, but as a combinatorial search problem. Thesis will be the machine behind the defining breakthroughs of the next decade.

Founders

• 
  Sergio Charles· Co-Founder & CEO

  Thesis will automate AI research. Maximally truth-seeking. Prev: AI R&D at Google X, Nvidia and Stanford's AI Lab, working with Andrew Ng and Chelsea Finn. B.S. Math & CS, M.S. Stats Stanford

  LinkedIn ↗
• 
  Luigi Charles· Founder

  Betting the farm that AI will become meaningful in the discovery of new science. Second time founder. Previously scaled stablecoin payments infrastructure from zero to billions. Columbia CS & Math.

  LinkedIn ↗

Product launches · 1 launch

• δ Thesis: Building the frontier of AI discovery ↗▲ 232Nov 11, 2025

  Making it possible for researchers anywhere to discover the next Transformer or invent the next AlphaFold.

Change history · 8 recorded

1. July 12, 2026
   • Description rewritten07:00 PM
   • Tags updated07:00 PM
2. June 27, 2026
   • Tags updated07:00 PM
3. June 10, 2026
   • Started hiring07:00 PM
4. June 9, 2026
   • Tags updated07:00 PM
   • Team grew from 2 to 307:00 PM
5. June 2, 2026
   • Pitch updated07:00 PM
   • Description rewritten07:00 PM